SIRT1 and cancer: Among the predicted targets of miR-29b such as signal transducer and activator of transcription 3 (Stat3), cyclin-dependent kinase 6 (CDK6), lysine demethylase 2A (KDM2A) and Sirtuin-1 (SIRT-1), SIRT-1 was reported to be associated with chemoresistance in cancers [31, 32, 33].