CYP27B1 and type 1 diabetes mellitus: Vitamin D-deficient status of the animals with T1D leads to an increase in CYP27B1 at both transcriptional (by 1.28-fold, p = 0.003) and translational (by 1.25-fold, p = 0.005) levels in the renal tissue (Figures 2(a) and 2(b)).