NHERF1 and colorectal carcinoma: Both CRC cell lines expressed low-steady-state levels of NHERF1 (Fig. 1b, c), while its mRNA transcript and protein levels was gradually increased in shβ-Cat-depleted CRC cells maintained under Dox (+Dox), achieving a peak of induction upon complete β-catenin knockdown (Fig. 1b, c).