Furthermore, lower-expression of miR-19a-3p may enhance the expression of MEF2A, β-MHC, BNP and TRPC1 in cardiomyocyte hypertrophy, which seemingly implies that lower-expression of miR-19a-3p mediated MEF2 signaling might be a cause of myocardial hypertrophy. This evidence concerns the gene TRPC1 and cardiac hypertrophy.