In detail, reconstituting the expression of either WFDC1 or IL-17D or a combination of both in SORBS2-knockdown ovarian cancer cells significantly reduced the number of metastatic nodules (Additional file 2: Figure S13c) and ascites volume compared with control SORBS2-knockdown ovarian cancer cells in vivo (Additional file 2: Figure S13d). Here, IL17D is linked to ovarian cancer.