We observed that stable overexpression of either WFDC1 or IL-17D or a combination of both (Additional file 2: Figure S13a, b) significantly decreased the invasive capacity of SORBS2-depleted ovarian cancer cells compared with control, revealed by Transwell chamber analysis (Fig. 5c) and wound healing analysis (Fig. 5d). Here, SORBS2 is linked to ovarian cancer.