SNP rs140849642 is located in the splice region of gene COL27A1, confirming the involvement of COL27A1, whereas markers rs202114540 and rs201749293 are in the coding regions of ALMS1 and HNF4A. Mutations in ALMS1 (centrosome and basal body associated protein) gene are known to cause Alström’s syndrome [53, 54]. The gene discussed is COL27A1; the disease is Alstrom syndrome.