To explore the molecular events downstream of hnRNP A2/B1, we first determined the expression of matrix metalloproteinases (MMPs) and STAT3, which are highly associated with the invasion and EMT of tumor cells and are modulated by hnRNP A2/B1 [10,17,18,19], after U251 cells were treated with β-asarone (60 μM) for different times. The gene discussed is STAT3; the disease is neoplasm.