Moreover, using databases (Cerami et al., 2012; Mizuno et al., 2009; SzaszSzász et al., 2016) that contain gene expression profiles of clinical cancer samples combined with patient outcomes, we found that overexpression of SPIN1 is correlated with poorer prognosis in patients with breast cancer, colorectal cancer and gastric cancer (Figure 6—figure supplement 2C–F). The gene discussed is SPIN1; the disease is colorectal cancer.