Patients with late clinical stage HIV based on WHO criteria or with a low CD4 count (less than 200 cells/μl) were found to be at a higher risk of developing TB in comparison to patients in early clinical stages of HIV (OR = 5.86 and 95% CI (1.88–17.96) and OR = 4.81 and 95% CI (1.57–15.26), respectively). The gene discussed is CD4; the disease is tuberculosis.