HLA-A and colorectal carcinoma: A phase I study, however, evaluating the combination of five HLA-A (human leukocyte antigen-A) antigens, each subcutaneously injected at separate sites in 18 HLA-A*2402-positive CRC patients, demonstrated a CR in one patient, stable disease over 4–7 months in six others, and a median OS of 13.5 months [125].