Assessing the inflammatory background main actors in psoriasis and NAFLD, many proinflammatory cytokines, such as IL-1β, TNF-α, and IL6, are in common and may create, sustain, and maintain the three stages of NAFLD, namely, inflammation, insulin resistance, and lipid accumulation [104]. The gene discussed is IL1B; the disease is metabolic dysfunction-associated steatotic liver disease.