In comparing the clinicopathological parameters between groups, including age, sex, lymph node metastasis, tumor grading and TNM staging, we found the level of CFIm25 was significantly associated with lymph node metastasis (Person’s chi-square test, P = 0.011) and TNM staging (Person’s chi-square test, P = 0.029), whereas age, sex, and tumor grade showed no statistical significance with CFIm25 (Table 1). This evidence concerns the gene NUDT21 and neoplasm.