EIF2AK3 and breast carcinoma: In agreement with regulation of PERK expression by NCOA3 we found that expression of PERK mRNA levels showed moderate positive relationship with the transcript levels of NCOA3 (Significance of correlation: R-value=0.391, p-value=2.5e-41, T-value=14.048, degrees of freedom=1095) in BRCA-TCGA datasets of breast cancer patients (Figure 2E).