Interestingly, the area of colonies of hMLH1(−) [5-FU(R)] was smaller than that of hMLH1(−) cells when 1× 103 cells were treated with 1μM of FTD (P < 0.05) (Figure 2D and 2E); these results were then confirmed by treating 1 × 104 cells with FTD (Figure 2F). The gene discussed is MLH1; the disease is frontotemporal dementia.