In this study, the elevated activities of P5CS and BADH in the parentally primed (T1D, T2D, T3D) plants may be resulted from up-regulation of P5CS and BADH expression, P5CS and BADH may be “trainable genes” playing roles in the transgenerational drought stress memory, or they could be regulated by the upstream signals which related genes have been trained. This evidence concerns the gene ALDH18A1 and type 1 diabetes mellitus.