TNFRSF25 and inflammatory bowel disease: Preclinical and clinical studies have clearly shown a fundamental role for the TL1A/DR3 cytokine/receptor pair in the pathogenesis of inflammatory diseases, including rheumatoid arthritis (13–15), diabetic retinopathy (16), pulmonary sarcoidosis (17), asthma (10, 18), and, especially, IBD (19).