CD40LG and HIV-1 infection: During early HIV-1 infection, IGHV1 and IGHV3 (respectively, 40.96% in PBMC and 51.22% in BM IgM libraries, and, respectively, 35.13% in BM and 33.8% in PBMC IgG libraries) were the most dominant while IGHV3 and IGHV4 (respectively, 38.42% in PBMC and 23.69% in BM IgM libraries), and specifically IGHV4 in IgG libraries (PBMC 27.89% and BM 28.32%) were the second most dominant (63).