OXTR and Abnormal emotional state: Regarding the results linked to the OXTR rs53576 gene polymorphism, participants who exhibited the GG genotype and experienced ET, PTSD, or both reported a series of impairments including emotional dysregulation and problematic attachment (Bradley et al., 2011), PTSD symptoms (Lucas-Thompson and Holman, 2013), symptoms of depression (McQuaid et al., 2013), lower levels of perceived social support, and internalized behavioral problems (Hostinar et al., 2014).