Elevated cyclin B1 expression levels are a common feature of various cancer models (Dutta et al., 1995; Mashal et al., 1996; Kushner et al., 1999; Yasuda et al., 2002; Grabsch et al., 2004) and associated with a poor prognosis for cancer patients (Soria et al., 2000). This evidence concerns the gene CCNB1 and cancer.