MC4R and Obesity: In the “preventative” study, along with the anti-obesity effect of SDV, we observed a decrease in the snout-to-anus length, which was absent in animals in the “treatment study.” This is noteworthy as there are reports in the literature that show that mutations in the Mc4r gene are associated with accelerated linear growth, which is disproportionate to the degree of obesity present (Martinelli et al., 2011).