Various mediators and cytokines such as tumor necrosis factor alpha (TNF-α), interleukin-6 (IL-6), and monocyte chemoattractant protein-1 (MCP-1), released by the accumulating inflammatory cells and adipocytes, may contribute to the development of metabolic syndrome, thus exacerbating the consequences of obesity3. This evidence concerns the gene CCL2 and metabolic syndrome.