IHC features: PAX-8, CK, EMA, ER and PR were strongly and diffusely expressed in the low-grade EmC component (Figure 5, 6, cases 3 and 4), whereas the UC component was diffusely positive for vimentin, focally positive for CK, EMA, and neuroendocrine markers such as synaptophysin, chromogranin A, and CD 56. The gene discussed is SYP; the disease is extraskeletal myxoid chondrosarcoma.