In the 10 COPD patients whose blood samples were collected again after 1-year treatment, FPR1 expression on neutrophil showed significant reduction (4.5 ± 1.7 vs. 5.8 ± 1.5 MFI, p = 0.003, Fig. 3g), while FPR2 expression on neutrophil showed elevation (18.1 ± 5.4 vs. 12.3 ± 9.8, p = 0.093) but the difference did not reach statistical significance. This evidence concerns the gene FPR1 and chronic obstructive pulmonary disease.