Significant differences in age, smoking, diabetes, hypertension (high blood pressure), hyperlipidemia, body mass index (BMI), obesity, menopause, family history, hemoglobin A1c, glucose, ApoA1, Apo B and ratios: total cholesterol/HDL, triglyceride/HDL, LDL/HDL, ApoB/ApoA1, Gensini score were observed between the CAD patients and control group (p < 0.01). The gene discussed is APOA1; the disease is diabetes mellitus.