ADA and rheumatoid arthritis: In reference to treatment holiday due to remission of bDMARDs, previous reports have demonstrated that IFX and ADA seem to have better potential for discontinuation compared to CZP or ETN, as shown in the BeSt, HIT HARD, and OPTIMA studies in early RA, and in the RRR and HONOR studies in established RA [26–33], which agree with our result.