To determine whether combinations of multiple biomarkers could improve the ability to detect Mtb-infected individuals, we examined the performance of all combinations of 23 biomarker responses (PDGF NIL, IL1β NIL, IL2 NIL, IL8,NIL, IL12p70 NIL, MCP-1 NIL, VEGF NIL, LIF NIL, IL2 Ag-NIL, IP10 Ag-NIL, IFN-γ Ag-NIL, MIG Ag-NIL, SCF Ag-NIL, b-NGF Ag-NIL, IL12-p40, MIF Ag-NIL, TRAIL Ag-NIL, IL2RaAg-NIL, IL13 Ag-NIL, TNF-β Ag-NIL, IL3 Ag–NIL, IFN-α2 Ag-NIL, LIF Ag-NIL) significantly differed between Mtb-infected cases (active TB n. Here, IL1B is linked to tuberculosis.