Results show (Table 4) that in response to Mtb antigen specific stimulation by ESAT-6/CFP-10, median concentrations of 14 analytes, namely IL-2, IP-10, IFN-γ, MIG, SCF, b-NGF, IL-12-p40, MIF, TRAIL, IL-2ra, TNF-β, IL-3, IFNα2, LIF and IL-13 were significantly different in the active TB and LTBI groups, compared to NON-TB patients. The gene discussed is MIF; the disease is tuberculosis.