32 Furthermore, ILC1s accumulate in the inflamed intestine of CD patients.30 There also seems to be some plasticity between ILC1 and ILC3 cells.32, 33 Thus, ILCs secreting both IFNγ and IL‐17 in response to IL‐23, or IFNγ and IL‐22 in response to IL‐12+IL‐18 have been reported.26, 34 It is thought that both NK cells and ILC1s depend on IL‐15 for their development,35, 36, 37, 38 which is in contrast to ILC2s and ILC3s, which rely on IL‐7 and are depleted in IL‐7Rα−/− mice.19, 39. Here, IFNG is linked to Cowden disease.