Several genes encoding core inflammasome components were all significantly expressed at higher levels in ACP tumours compared with control tissues, including NLRP1 (6.4-fold), NLRP3 (4.8-fold), NLRC4 (4.8-fold), CASP1 (5-fold) and PYCARD (4-fold) [Suppl. The gene discussed is PYCARD; the disease is neoplasm.