NR1H4 and hepatocellular carcinoma: In addition, in human hepatoma Huh‐7 cells, compound‐T1 concentration‐dependently rescued the CDCA‐induced reduction in apolipoprotein A‐I production, and the ED50 value was 1.8 nmol·L−1, which was a similar concentration to the IC50 value in the human FXR antagonism reporter gene assay (Table 1).