The reduction of H3K4me3 and H3K9ac levels at mutant TERT promoters was similarly observed in BRAF-mutant, TERT (−146C > T) or TERT (−124C > T) melanoma cell lines, UACC257, A375, WM793, and Malme-3M, following si-BRAF treatment [20]. This evidence concerns the gene BRAF and melanoma.