ABL1 and chronic myelogenous leukemia, BCR-ABL1 positive: The strategies here reported demonstrate clearly that the study of MRD in CML by the BCR-ABL1 DNA-based patient-specific probe is feasible: FISH and MinION steps, respectively, together with ddPCR analysis, greatly reduce the complexity that has impeded the use of “personalized monitoring” of CML in clinical practice.