What is noteworthy is that, NCBI GEO gene expression database of TECs in colorectal cancer and lymphoma also verified the specific high expression of 7 out of these 12 ECM associated genes in TECs from colorectal cancer and lymphoma, i.e. SPON2, BMP-1, FN1, POSTN, THBS2, VCAN and AEBP1. The gene discussed is THBS2; the disease is colorectal cancer.