Similarly in the lymphoma ECs, 7 genes ranked in the top 2000 genes, i.e., insulin like growth factor binding protein 7 (IGFBP7, No.83), laminin subunit alpha 4 (LAMA4, No.106), laminin subunit beta 1 (LAMB1, No.188), tissue inhibitor of metalloproteinase 3 (TIMP3, No.509), FN1 (No.1025), secreted protein acidic and cysteine rich (SPARC, No.1146) and POSTN (No.1890) (Figure 13B). The gene discussed is IGFBP7; the disease is lymphoma.