However, in our previous studies, due to (1) the lack of side-by-side follow-up comparisons of DcR3 with commonly used biomarkers for sepsis, such as PCT, IL6 and CRP; and (2) the lack of a follow-up study of DcR3 with the course of sepsis, the value of DcR3 in clinical practice cannot be established. The gene discussed is CRP; the disease is Sepsis.