Finally, we detected the cleavage of Plk1 in three other cell lines, JURLMK1, another CML cell line, SKM1 an MDS/AML (myelodysplastic syndrome/acute myeloid leukemia) cell line and U266, a multiple myeloma cell line (Figure 1E). Here, PLK1 is linked to chronic myelogenous leukemia, BCR-ABL1 positive.