Interestingly, among the deregulated proteins associated to Alzheimer’s disease, we found previously reported AD-associated proteins, including the accumulation of GATA4 and Chromogranin-A [24–27], or MBL2 [28], whose over-expression has been described in the surrounding of blood vessels in AD brain patients. Here, GATA4 is linked to early-onset autosomal dominant Alzheimer disease.