HCRT and migraine disorder: About the orexinergic innervation role in the migraine pathophysiology, axons immunoreactive to orexin/hypocretin A are reported as present at low density in lateral posterior (LP), and lateral dorsal (LD) nuclei of thalamus, and most median part of thalamic posterior complex (Po), and at very low density in ventral posterior median nucleus of thalamus (VPM) and most lateral part of Po (52).