NAMPT and preeclampsia: Notably, the rs1319501 SNP (T-423C) in the promoter region and the rs3801266 SNP (A/G) in the intron 1 of NAMPT gene were shown to be associated with the susceptibility to preeclampsia (Luizon et al., 2015), and to affect plasma visfatin/NAMPT levels in patients who were non-responsive to total antihypertensive therapy (Luizon et al., 2017b).