CPT1B and asthma: By contrast, in the chronic OVA (non-alum) model of asthma, where mast cells play roles both in the early inflammatory phase (via degranulation) and also in the later airway remodelling phases of disease, whilst reduced levels of mast cells were found in the lungs of ES-62-treated mice12, this was not associated with a significant decrease in BALF levels of MCPT-1 in the chronic phase of disease.