KIR3DL2 and melanoma: For instance, we found recurrent breakpoints >25 kb apart that flanked genes in the preferentially expressed antigen in melanoma family (PRAMEF), the histone cluster 2, defensin betas, the C-C motif chemokine ligands, and killer cell immunoglobulin-like receptors (Fig. 3b and Supplementary Data 3 and 4).