Studies implicating the association of tumoral cholesterol biosynthesis and cholesterol uptake by lipoprotein receptors such as low‐density lipoprotein receptor (LDLR) and scavenger receptor B1 (SRB1) in the development of CRPC have proposed a potential role for cholesterol in prostate cancer progression (Kim et al, 2014; Schorghofer et al, 2015; Furuya et al, 2016). This evidence concerns the gene SCARB1 and prostate cancer.