MEG3 and cancer: These included known cases of lncRNAs involved in different cancers, such as GAS5, DLEU2, PART1 and MEG3. We expanded this analysis to The Cancer Genome Atlas (TCGA) RNA-Seq data available for 24 different cancer types and over nine thousand samples [55] and verified that 443 pcRNAs were annotated and differentially expressed in this dataset (Additional file 4: Figure S17b).