Abetalipoproteinemia (ABL; OMIM 200100) and familial hypobetalipoproteinemia (FHBL; OMIM 615558) are rare genetic disorders affecting packaging and transport of apolipoprotein (apo) B-containing lipoprotein particles, which are essential for the absorption and trafficking of cholesterol and triglycerides [1]. This evidence concerns the gene APOB and familial hypobetalipoproteinemia 1.