VIM and viral infectious disease: Viral infection altershost cell architecture similarly, as parvovirus in mice10 but other pathogens also affects vimentin distribution ininfected cells, with similar perivacuolar distribution, as in Salmonellainfections.11 Proteomics studies inexperimental models of T.cruzi infection had shown higher plasmalevels of vimentin related to disease severity,12 which can offer to the immune response intracellular filaments forantibody production.