VIM and American trypanosomiasis: Our data were similar to those findings and anti-vimentin antibodies inducedduring T.cruzi infection could be a marker of active disease in thehost and its levels could also justify drug therapy in American Trypanosomiasischronic infection, as a large group of asymptomatic or indeterminate patients wouldbe submitted to treatment with frequent adverse reactions of the available drugs.Anti-vimentin antibodies could be a marker of cardiac muscle cell damage, appearingin American Trypanosomiasis patients during active muscle cell damage.