Other host factors more recently described to be involved in regulating cellular proteins important for HCV entry, including EGFR, LDLR, NPC1L1, TfR1, SRFBP1, as well as epithelial-to-mesenchymal transition (EMT) markers such as E-cadherin and vimentin were analyzed, but none of them were differentially expressed between tumor and nontumorous tissue (S3 Fig). The gene discussed is NPC1L1; the disease is neoplasm.