EDNRA and dementia: Dementia-associated autoantibodies directed against G-protein coupled receptors (GPCR-AABs) such as those directed against the α1-adrenergic (α1-AABs), β2-adrenergic (β2-AABs) and endothelin A receptor (ETA-AABs) related to their target (extracellular receptor loop) with the specific epitope.