Drugs that are OATP1B1/1B3 inhibitors (e.g., gemfibrozil, cyclosporine A, rifampicin and ritonavir) may cause clinically significant adverse effects, such as myopathy, when co-administered with lipid-lowering statins, which are substrates of OATPs [54,55,56,57]. This evidence concerns the gene SLCO1B1 and myopathy.