OATP1B1 and OATP1B3 mediate the hepatic uptake of many clinically important drugs (e.g., the 3-hydroxy-3-methylglutaryl-coenzyme (HMG-CoA) reductase inhibitors, anti-diabetics, anti-cancers) and endogenous compounds (e.g., bile acids) [6]. This evidence concerns the gene SLCO1B1 and cancer.