Moreover, miR‐140‐5p could inhibit angiogenesis in a rat model of ischaemia by targeting VEGFA, which may be beneficial for cerebral ischaemia treatment.8 Additionally, it was demonstrated during our study that the mRNA and protein expressions of Wnt1, β‐catenin, TCF‐4 and E‐cadherin were increased in other groups as compared with the model group. The gene discussed is TCF4; the disease is ischemia.