VDR and cancer: Potential anti‐cancer effects of vitamin D are via free 1,25OH2D interacting with the vitamin D receptor within tissues resulting in reduced angiogenesis, metastasis, cell invasion, inflammation, and proliferation as well as upregulation of apoptosis.8 Levels of 1,25OH2D are assumed to be correlated with circulating 25OHD, but this is not necessarily the case.