At first we integrated clinico-morphological parameters known to affect PCa recurrence, i.e., PSA level, Gleason sum, tumor stage, age and resection margins (R0 vs. R1) in our base line model and obtained a sensitivity of 77.8% and a specificity of 75.0% to separate PCa without from those with recurrence. Here, KLK3 is linked to posterior cortical atrophy.