One miRNA, miR-548p, which was highly down-regulated in FLC (Δlog2 = −4.41, padj = 3.36 × 10−11), had target RNA transcripts predicted by DIANA that were previously described to be over-expressed in FLC tumor samples [7], in particular, the Frizzled 10 receptor (FZD10), a receptor of the wnt family. Here, FZD10 is linked to fibrolamellar hepatocellular carcinoma.